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Chemical structure of Amyloid β/A4 Protein Precursor₇₇₀ (667-676)

GA20718

Amyloid β/A4 Protein Precursor₇₇₀ (667-676)

Also known as (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(1S)-1-carboxy-4-(diaminomethylideneamino)butyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid

The peptide substrate APP (667-676), SEVKMDAEFR, corresponds to the wild-type amyloid precursor protein (APP) β-secretase cleavage site· SEVKMDAEFR has been used for assaying β-secretase activity

ChemicalCAS252256-37-4MW1211.36FormulaC51H82N14O18S
CAS number
252256-37-4
Molecular weight
1211.36
Formula
C51H82N14O18S
Solubility
Soluble in DMSO
InChIKey
BLKDQJZDKNYVBO-MWHZAZASSA-N
Catalogue number
GA20718
Brand
GLPBIO
Computed properties PubChem CID 9898450 · XLogP -8.7 · TPSA 573 Ų · H-bond donors 18
XLogP
-8.7
TPSA
573 Ų
H-bond donors
18
H-bond acceptors
22
Rotatable bonds
42
Heavy atoms
84

SMILES C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)N

Computed descriptors from PubChem (CID 9898450), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.