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Chemical structure of 7-Dimethylamino-1-N-maleinimidomethyl-phenoxazone(-3)

GA20446

7-Dimethylamino-1-N-maleinimidomethyl-phenoxazone(-3)

Also known as 1-[[7-(dimethylamino)-3-oxophenoxazin-1-yl]methyl]pyrrole-2,5-dione

A superior thiol-reactive fluorophore for studying protein conformational changes· The fluorescent compound was used to monitor conformational changes underlying voltage-sensing in the Shaker potassium channel and to report subtle differences between aqueous positions in purified preparations of the β?-adrenergic receptor

ChemicalCAS848674-69-1MW349.35FormulaC19H15N3O4
CAS number
848674-69-1
Molecular weight
349.35
Formula
C19H15N3O4
Solubility
Soluble in DMSO
InChIKey
QNBVIPQDRLSEJB-UHFFFAOYSA-N
Catalogue number
GA20446
Brand
GLPBIO
Computed properties PubChem CID 95566098 · XLogP 0.7 · TPSA 79.3 Ų · H-bond donors 0
XLogP
0.7
TPSA
79.3 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
26

SMILES CN(C)C1=CC2=C(C=C1)N=C3C(=CC(=O)C=C3O2)CN4C(=O)C=CC4=O

Computed descriptors from PubChem (CID 95566098), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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