![Chemical structure of 6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH2](https://pub-57aadb51ed7d490d8ab1a98862827725.r2.dev/GA20442.png)
GA20442
6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH2
Also known as (2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanoylamino]pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-6-[[2-[7-(dimethylamino)-2-oxochromen-4-yl]acetyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH? (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3)· This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover· It has a kcat/Km value of 2·14 x 10? M?¹s?¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission)· Therefore this compound is a suitable tool for high-throughput inhibitor screening
- CAS number
- 945414-97-1
- Molecular weight
- 1598.87
- Formula
- C78H111N21O16
- Solubility
- Soluble in DMSO
- InChIKey
- SCMRYUWYMBCNED-AHVFAWDSSA-N
- Catalogue number
- GA20442
- Brand
- GLPBIO
Computed properties PubChem CID 137199812 · XLogP 3 · TPSA 549 Ų · H-bond donors 14
- XLogP
- 3
- TPSA
- 549 Ų
- H-bond donors
- 14
- H-bond acceptors
- 22
- Rotatable bonds
- 45
- Heavy atoms
- 115
SMILES CCC[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCCCNC(=O)CC3=CC(=O)OC4=C3C=CC(=C4)N(C)C)C(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCCN)NC(=O)[C@@H]6CCCN6C(=O)[C@H](CCCN=C(N)N)NC(=O)CCCCCNC7=CC=C(C8=NON=C78)[N+](=O)[O-]
Computed descriptors from PubChem (CID 137199812), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il