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Chemical structure of 4-(Fmoc-hydrazino)-benzoic acid

GA20406

4-(Fmoc-hydrazino)-benzoic acid

Also known as 4-[2-(9H-fluoren-9-ylmethoxycarbonyl)hydrazinyl]benzoic acid

This linker which is stable to acid and bases is cleaved with high specificity under mild oxidative conditions in the presence of base and a nucleophile, yielding a range of C-terminal functionalities· The linker may be used to synthesize fully or partially protected peptides for fragment coupling·See also D-2560

ChemicalCAS214475-53-3MW374.4FormulaC22H18N2O4
CAS number
214475-53-3
Molecular weight
374.4
Formula
C22H18N2O4
Solubility
Soluble in DMSO
InChIKey
MLVJMSRGLQCZDE-UHFFFAOYSA-N
Catalogue number
GA20406
Brand
GLPBIO
Computed properties PubChem CID 2756155 · XLogP 4.5 · TPSA 87.7 Ų · H-bond donors 3
XLogP
4.5
TPSA
87.7 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
28

SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NNC4=CC=C(C=C4)C(=O)O

Computed descriptors from PubChem (CID 2756155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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