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Chemical structure of (Val³⁴)-Amyloid β-Protein (1-40)

GA20341

(Val³⁴)-Amyloid β-Protein (1-40)

Cerebral amyloid angiopathy (CAA) is a common finding in Alzheimer's disease in which amyloid-Aβ vascular deposits are featured in >80% of the cases· Mutations in the positions 21-23 (e·g· Dutch mutation E22Q) are primarily associated with CAA, although they manifest with strikingly different clinical phenotypes: cerebral hemorrhage or dementia· The Piedmont L34V Aβ mutant, located outside this hot spot, shows a similar hemorrhagic phenotype, albeit less aggressive than the widely studied Dutch variant

ChemicalCAS1678415-83-2MW4315.84FormulaC193H293N53O58S
CAS number
1678415-83-2
Molecular weight
4315.84
Formula
C193H293N53O58S
Solubility
Soluble in DMSO
Catalogue number
GA20341
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.