GA20309
(Thr²)-Amyloid β-Protein (1-42)
A mutation very close to the β-secretase cleavage site of APP· The Icelandic mutation A2T of Aβ42 turned out to be less pathogenic than the native sequence· The precursor APP A673T was the first APP variant discovered in humans reducing the risk of Alzheimer's disease· A2T as well affects γ-secretase cleavage, the mutant was an inefficient substrate in a cell-based assay of the enzyme
ChemicalMW4544.13FormulaC204H313N55O61S
- CAS number
- —
- Molecular weight
- 4544.13
- Formula
- C204H313N55O61S
- Solubility
- Soluble in DMSO
- Catalogue number
- GA20309
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il