GA20259
(Nle³⁵)-Amyloid β-Protein (1-40)
The reactive thioether of Met³? is crucial for the activity of Aβ 1-40 and Aβ 1-42· Due to the replacement of Met by inert Nle, M35Nle Aβ 1-40 was no longer toxic to cultured hippocampal neurons and had little effect on the level of protein carbonyl residues· The Nle peptide showed the same propensity to aggregate, whereas sulfoxide formation hindered the required conformational transition from random coil to β-sheet
ChemicalCAS1802086-31-2MW4311.83FormulaC195H297N53O58
- CAS number
- 1802086-31-2
- Molecular weight
- 4311.83
- Formula
- C195H297N53O58
- Solubility
- Soluble in DMSO
- Catalogue number
- GA20259
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il