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Chemical structure of (Lys²²)-Amyloid β-Protein (1-40)

GA20244

(Lys²²)-Amyloid β-Protein (1-40)

The Italian mutation of β-amyloid 1-40 (E22K) aggregates more rapidly than the wild-type sequence 1-40· It showed increased neurotoxicity, which (according to a solid-phase NMR-study of Masuda et al·) may be due to the salt bridge formed between Lys²² and Asp²³ in the minor conformer· As the Arctic, Flemish, and Dutch mutants, the Italian mutant is degraded considerably more slowly than wild-type Aβ by neprilysin

ChemicalCAS302905-01-7MW4328.92FormulaC195H300N54O56S
CAS number
302905-01-7
Molecular weight
4328.92
Formula
C195H300N54O56S
Solubility
Soluble in DMSO
Catalogue number
GA20244
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.