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Chemical structure of (Gly²¹)-Amyloid β-Protein (1-40)

GA20197

(Gly²¹)-Amyloid β-Protein (1-40)

Contrary to β-amyloid peptides mutated at position 22 (Dutch, Italian, Arctic mutants) the Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity· In the studies of Betts and Tsubuki, A21G was degraded significantly more slowly by neprilysin than the wild-type Aβ 1-40 and the E22 mutants· The relative resistance to proteolytic degradation may account for the pathogenicity of the Aβ mutant

ChemicalCAS154362-03-5MW4315.84FormulaC193H293N53O58S
CAS number
154362-03-5
Molecular weight
4315.84
Formula
C193H293N53O58S
Solubility
Soluble in DMSO
Catalogue number
GA20197
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.