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Chemical structure of Enkephalin, pen(2,5)-4-chloro-phe(4)-

GA20144

Enkephalin, pen(2,5)-4-chloro-phe(4)-

Also listed as (D-Pen²,p-chloro-Phe⁴,D-Pen⁵)-Enkephalin

The introduction of a chloro substituent in para-position of the Phe? aromatic ring of DPDPE led to a compound with 5 times higher δ-selectivity than the parent peptide due to a 5-fold increased δ-receptor affinity· For this reason, (Cpa?)-DPDPE may prove to be the ligand of choice for studying the properties of δ-opioid receptors

ChemicalCAS122507-47-5MW680.25FormulaC30H38ClN5O7S2
CAS number
122507-47-5
Molecular weight
680.25
Formula
C30H38ClN5O7S2
Solubility
Soluble in DMSO
InChIKey
VTVUYFFDQHWCTJ-WMIMKTLMSA-N
Catalogue number
GA20144
Brand
GLPBIO
Computed properties PubChem CID 159564 · XLogP 0 · TPSA 251 Ų · H-bond donors 7
XLogP
0
TPSA
251 Ų
H-bond donors
7
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
45

SMILES CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=C(C=C2)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)C

Computed descriptors from PubChem (CID 159564), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.