GA20095
(Des-Glu²²)-Amyloid β-Protein (1-40)
The Osaka mutation was the first deletion-type mutation to be identified in APP and Aβ·The Aβ E22delta mutant is more resistant to degradation by two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme· Synthetic mutant Aβ showed unusual aggregation properties with enhanced oligomerization but no fibrillization· It also inhibited hippocampal long-term potentiation more efficiently than wild-type Aβ· A transgenic mouse model containing APP with the E693delta mutation has been developed· APP(OSK)-Tg mice exhibit intraneuronal Aβ E22delta oligomers and memory impairment as early as eight months of age
ChemicalCAS1678416-36-8MW4200.75FormulaC189H288N52O55S
- CAS number
- 1678416-36-8
- Molecular weight
- 4200.75
- Formula
- C189H288N52O55S
- Solubility
- Soluble in DMSO
- Catalogue number
- GA20095
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il