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Chemical structure of DesBr-NPB-23 (human)

GA20093

DesBr-NPB-23 (human)

Also listed as (Des-Bromo)-Neuropeptide B (1-23) (human)

(Des-Bromo)-Neuropeptide B (1-23) (human), a neuropeptide B derivative, has been shown to inhibit forskolin-induced cAMP production in CHO- cells expressing either bovine or human G-protein-coupled receptor GPR7 to a similar extent as neuropeptide B (human)· The IC?? values for bovine and human GPR7 are 3·5 nM and 0·58 nM, respectively

ChemicalCAS434897-64-0MW2348.65FormulaC107H162N30O30
CAS number
434897-64-0
Molecular weight
2348.65
Formula
C107H162N30O30
Solubility
Soluble in DMSO
InChIKey
IIQJVSOPJNZYSE-MFCZVQBRSA-N
Catalogue number
GA20093
Brand
GLPBIO
Computed properties PubChem CID 102601361 · XLogP -6.3 · TPSA 949 Ų · H-bond donors 35
XLogP
-6.3
TPSA
949 Ų
H-bond donors
35
H-bond acceptors
34
Rotatable bonds
72
Heavy atoms
167

SMILES C[C@@H](C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCCN)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)N

Computed descriptors from PubChem (CID 102601361), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.