C60263
Conjugated BIN1 Rabbit mAb
Conjugated BIN1 Rabbit mAb (catalogue number C60263) is a recombinant rabbit-derived conjugated primary antibody, reactive with Human samples. It targets Myc box-dependent-interacting protein 1 (BIN1): Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human
- Conjugate
- AF Dye
- UniProt ID
- O00499
- Gene
- BIN1
- Target organism
- Homo sapiens
- Catalogue number
- C60263
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Myc box-dependent-interacting protein 1 (BIN1) · Homo sapiens
Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis. Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production. In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates.
Subcellular location: Nucleus; Cytoplasm; Endosome; Cell membrane, sarcolemma, T-tubule
Tissue specificity: Ubiquitous. Highest expression in the brain and muscle. Expressed in oligodendrocytes. Isoform IIA is expressed only in the brain, where it is detected in the gray matter, but not in the white matter. Isoform BIN1 is widely expressed with highest expression in skeletal muscle
Sequence length: 593 aa · 64699 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il