C59924
Conjugated Villin-1 Rabbit mAb
Conjugated Villin-1 Rabbit mAb (catalogue number C59924) is a recombinant rabbit-derived conjugated primary antibody, reactive with Human samples. It targets Villin-1 (VIL1): Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human
- Conjugate
- AF Dye
- UniProt ID
- P09327
- Gene
- VIL1
- Target organism
- Homo sapiens
- Catalogue number
- C59924
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Villin-1 (VIL1) · Homo sapiens
Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity.
Subcellular location: Cytoplasm, cytoskeleton; Cell projection, lamellipodium; Cell projection, ruffle; Cell projection, microvillus; Cell projection, filopodium tip; Cell projection, filopodium
Tissue specificity: Specifically expressed in epithelial cells. Major component of microvilli of intestinal epithelial cells and kidney proximal tubule cells. Expressed in canalicular microvilli of hepatocytes (at protein level)
Sequence length: 827 aa · 92695 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il