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Conjugated GEF H1 Rabbit mAb

C59765

Conjugated GEF H1 Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
Q92974
Gene
ARHGEF2
Target organism
Homo sapiens
Catalogue number
C59765
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Rho guanine nucleotide exchange factor 2 (ARHGEF2) · Homo sapiens

Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases, which was uniquely reported in PubMed:9857026. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras-GTPases.

Subcellular location: Cytoplasm, cytoskeleton; Cytoplasm; Cell junction, tight junction; Golgi apparatus; Cytoplasm, cytoskeleton, spindle; Cell projection, ruffle membrane; Cytoplasmic vesicle

Sequence length: 986 aa · 111543 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.