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Conjugated SET Rabbit mAb

C59709

Conjugated SET Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
Q01105
Gene
SET
Target organism
Homo sapiens
Catalogue number
C59709
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Protein SET (SET) · Homo sapiens

Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A.

Subcellular location: Cytoplasm, cytosol; Endoplasmic reticulum; Nucleus, nucleoplasm

Tissue specificity: Widely expressed. Low levels in quiescent cells during serum starvation, contact inhibition or differentiation. Highly expressed in Wilms' tumor

Sequence length: 290 aa · 33489 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.