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Conjugated Presenilin 1 Rabbit mAb

C59665

Conjugated Presenilin 1 Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
P49768
Gene
PSEN1
Target organism
Homo sapiens
Catalogue number
C59665
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Presenilin-1 (PSEN1) · Homo sapiens

Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

Subcellular location: Endoplasmic reticulum; Endoplasmic reticulum membrane; Golgi apparatus membrane; Cytoplasmic granule; Cell membrane; Cell projection, growth cone; Early endosome; Early endosome membrane; Cell project

Tissue specificity: Detected in azurophile granules in neutrophils and in platelet cytoplasmic granules (at protein level). Expressed in a wide range of tissues including various regions of the brain, liver, spleen and lymph nodes

Sequence length: 467 aa · 52668 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.