Conjugated CLOCK Rabbit mAb

Target background

Target: Circadian locomoter output cycles protein kaput (CLOCK) · Homo sapiens

Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function.

Subcellular location: Nucleus; Cytoplasm; Cytoplasm, cytosol

Tissue specificity: Hair follicles (at protein level). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine, colon, leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in testis and skeletal muscle.

Sequence length: 846 aa · 95304 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.