
C59275
Conjugated ASPP2 Rabbit mAb
Conjugated ASPP2 Rabbit mAb (catalogue number C59275) is a recombinant rabbit-derived conjugated primary antibody, reactive with Human samples. It targets Apoptosis-stimulating of p53 protein 2 (TP53BP2): Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human
- Conjugate
- AF Dye
- UniProt ID
- Q13625
- Gene
- TP53BP2
- Target organism
- Homo sapiens
- Catalogue number
- C59275
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Apoptosis-stimulating of p53 protein 2 (TP53BP2) · Homo sapiens
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of NAE1 to conjugate NEDD8 to CUL1, and thereby decreases NAE1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42
Subcellular location: Cytoplasm, perinuclear region; Nucleus
Tissue specificity: Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines
Sequence length: 1128 aa · 125616 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il