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Conjugated NEDD8 Rabbit mAb

C59245

Conjugated NEDD8 Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
Q15843
Gene
NEDD8
Target organism
Homo sapiens
Catalogue number
C59245
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Ubiquitin-like protein NEDD8 (NEDD8) · Homo sapiens

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity.

Subcellular location: Nucleus

Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes

Sequence length: 81 aa · 9072 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.