
C58892
Conjugated GRK2 Rabbit mAb
Human Mouse Rat Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Conjugate
- AF Dye
- UniProt ID
- P25098
- Gene
- GRK2
- Target organism
- Homo sapiens
- Catalogue number
- C58892
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: G protein-coupled receptor kinase 2 (GRK2) · Homo sapiens
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor internalization, and signaling events leading to their desensitization. Phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Phosphorylates catecholamine-activated ADRB2 to regulate physiological cardiomyocyte contraction rate responses.
Subcellular location: Cytoplasm; Cell membrane; Cell projection, cilium membrane; Postsynapse; Presynapse
Tissue specificity: Expressed in peripheral blood leukocytes
Sequence length: 689 aa · 79574 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il