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Conjugated GRK2 Rabbit mAb

C58892

Conjugated GRK2 Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
P25098
Gene
GRK2
Target organism
Homo sapiens
Catalogue number
C58892
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: G protein-coupled receptor kinase 2 (GRK2) · Homo sapiens

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor internalization, and signaling events leading to their desensitization. Phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Phosphorylates catecholamine-activated ADRB2 to regulate physiological cardiomyocyte contraction rate responses.

Subcellular location: Cytoplasm; Cell membrane; Cell projection, cilium membrane; Postsynapse; Presynapse

Tissue specificity: Expressed in peripheral blood leukocytes

Sequence length: 689 aa · 79574 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.