C58743
Conjugated p27 KIP 1 Rabbit mAb
Human Rat Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Rat
- Conjugate
- AF Dye
- UniProt ID
- P46527
- Gene
- CDKN1B
- Target organism
- Homo sapiens
- Catalogue number
- C58743
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Cyclin-dependent kinase inhibitor 1B (CDKN1B) · Homo sapiens
Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichiometry
Subcellular location: Nucleus; Cytoplasm; Endosome
Tissue specificity: Expressed in kidney (at protein level). Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney
Sequence length: 198 aa · 22073 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il