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Conjugated RNF20 Rabbit mAb

C58569

Conjugated RNF20 Rabbit mAb

Human Mouse Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse
Conjugate
AF Dye
UniProt ID
Q5VTR2
Gene
RNF20
Target organism
Homo sapiens
Catalogue number
C58569
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: E3 ubiquitin-protein ligase BRE1A (RNF20) · Homo sapiens

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory.

Subcellular location: Nucleus

Tissue specificity: Expressed in the normal brain and also in malignant gliomas (at protein level)

Sequence length: 975 aa · 113662 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.