C58560
Conjugated Bax Rabbit mAb
Human Mouse Rat Hamster Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat Hamster
- Conjugate
- AF Dye
- UniProt ID
- Q07812
- Gene
- BAX
- Target organism
- Homo sapiens
- Catalogue number
- C58560
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Apoptosis regulator BAX (BAX) · Homo sapiens
Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis
Subcellular location: Mitochondrion outer membrane; Cytoplasm; Nucleus
Tissue specificity: Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin.
Sequence length: 192 aa · 21184 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il