C58515
Conjugated DSG1 Rabbit mAb
Human Mouse Rat Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Conjugate
- AF Dye
- UniProt ID
- Q02413
- Gene
- DSG1
- Target organism
- Homo sapiens
- Catalogue number
- C58515
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Desmoglein-1 (DSG1) · Homo sapiens
A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Promotes differentiation of keratinocytes via interaction with ERBIN. Reduces activation of RAS/ERK signaling pathways in keratinocytes via promoting ERBIN localization to the cell membrane and its interaction with SHOC2, this competitively reduces the formation of RAS-SHOC2 ERK-activating complexes. Mediates the interaction between the desmosome and COP9 signalosome complex (CSN) protein complex.
Subcellular location: Cell membrane; Cell junction, desmosome; Cytoplasm; Nucleus
Tissue specificity: Expressed in all suprabasal layers of the epidermis, with the highest expression seen in the granular layer (at protein level). Expressed in the suprabasal esophageal epithelium (at protein level)
Sequence length: 1049 aa · 113748 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il