
C57354
Conjugated TRIF Rabbit mAb
Conjugated TRIF Rabbit mAb (catalogue number C57354) is a rabbit-derived conjugated primary antibody, reactive with Human, Mouse, Rat samples. It targets TIR domain-containing adapter molecule 1 (TICAM1): Involved in innate immunity against invading pathogens. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human, Mouse, Rat
- Conjugate
- AF Dye
- UniProt ID
- Q8IUC6
- Gene
- TICAM1
- Target organism
- Homo sapiens
- Catalogue number
- C57354
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: TIR domain-containing adapter molecule 1 (TICAM1) · Homo sapiens
Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Subcellular location: Cytoplasmic vesicle, autophagosome; Cytoplasm, cytosol; Mitochondrion
Tissue specificity: Ubiquitously expressed but with higher levels in liver
Sequence length: 712 aa · 76422 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il