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Conjugated PRAME Rabbit mAb

C57320

Conjugated PRAME Rabbit mAb

Conjugated PRAME Rabbit mAb (catalogue number C57320) is a rabbit-derived conjugated primary antibody, reactive with Human, Mouse samples. It targets Melanoma antigen preferentially expressed in tumors (PRAME): Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Conjugated Primary AntibodyHostRabbitConjugateAF Dye
Host / source
Rabbit
Reactivity
Human, Mouse
Conjugate
AF Dye
UniProt ID
P78395
Gene
PRAME
Target organism
Homo sapiens
Catalogue number
C57320
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Melanoma antigen preferentially expressed in tumors (PRAME) · Homo sapiens

Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation. The CRL2(PRAME) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding. In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin regulation.

Subcellular location: Nucleus; Chromosome; Cytoplasm; Golgi apparatus; Cell membrane

Tissue specificity: Expressed in testis. Detected in samples of kidney, brain and skin

Sequence length: 509 aa · 57890 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.