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Conjugated DBC 1 Rabbit mAb

C57253

Conjugated DBC 1 Rabbit mAb

Conjugated DBC 1 Rabbit mAb (catalogue number C57253) is a rabbit-derived conjugated primary antibody, reactive with Human samples. It targets Cell cycle and apoptosis regulator protein 2 (CCAR2): Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local… Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Conjugated Primary AntibodyHostRabbitConjugateAF Dye
Host / source
Rabbit
Reactivity
Human
Conjugate
AF Dye
UniProt ID
Q8N163
Gene
CCAR2
Target organism
Homo sapiens
Catalogue number
C57253
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Cell cycle and apoptosis regulator protein 2 (CCAR2) · Homo sapiens

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.

Subcellular location: Nucleus; Cytoplasm; Cytoplasm, cytoskeleton, spindle

Tissue specificity: Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues

Sequence length: 923 aa · 102902 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.