
C57234
Conjugated Caspase 11 Rabbit mAb
Conjugated Caspase 11 Rabbit mAb (catalogue number C57234) is a rabbit-derived conjugated primary antibody, reactive with Human, Mouse, Rat samples. It targets Caspase-4 (Casp4): Inflammatory caspase that acts as the effector of the non-canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human, Mouse, Rat
- Conjugate
- AF Dye
- UniProt ID
- P70343
- Gene
- Casp4
- Target organism
- Mus musculus
- Catalogue number
- C57234
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Caspase-4 (Casp4) · Mus musculus
Inflammatory caspase that acts as the effector of the non-canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. Also indirectly activates the NLRP3 and NLRP6 inflammasomes. Acts as a thiol protease that cleaves a tetrapeptide after an Asp residue at position P1: catalyzes cleavage of CGAS and GSDMD. In contrast to its human ortholog, does not cleave IL18.
Subcellular location: Cytoplasm, cytosol; Cytoplasm; Endoplasmic reticulum membrane; Mitochondrion; Inflammasome; Secreted
Tissue specificity: Widely expressed, including in thymus, lung and spleen (at protein level). Very low levels, if any, in the brain
Sequence length: 373 aa · 42742 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il