Conjugated FXR1 Rabbit mAb

Target background

Target: RNA-binding protein FXR1 (FXR1) · Homo sapiens

mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for various processes, such as neurogenesis, muscle development and spermatogenesis. Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors.

Subcellular location: Cytoplasm, Cytoplasmic ribonucleoprotein granule; Cytoplasm, Stress granule; Cytoplasm; Cell projection, dendrite; Cell projection, dendritic spine; Cell projection, axon; Nucleus envelope; Postsynaps

Tissue specificity: Expressed in all tissues examined including heart, brain, kidney and testis. In brain, present at high level in neurons and especially in the Purkinje cells at the interface between the granular layer and the molecular layer (at protein level)

Sequence length: 621 aa · 69721 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.