Conjugated Cenexin1 / ODF2 Rabbit mAb

Target background

Target: Outer dense fiber protein 2 (ODF2) · Homo sapiens

Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes.

Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cell projection, cilium; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Cytoplasm, cytoskeleton, spi

Tissue specificity: Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails

Sequence length: 829 aa · 95401 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.