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Conjugated PIAS1 + PIAS2 Rabbit mAb

C56171

Conjugated PIAS1 + PIAS2 Rabbit mAb

Human Mouse Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Conjugate
AF Dye
UniProt ID
O75925
Gene
PIAS1
Target organism
Homo sapiens
Catalogue number
C56171
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: E3 SUMO-protein ligase PIAS1 (PIAS1) · Homo sapiens

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Catalyzes sumoylation of various proteins, such as CEBPB, MRE11, MTA1, PTK2, PML and ZNF76. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Subcellular location: Nucleus; Nucleus speckle; Nucleus, PML body; Cytoplasm, cytoskeleton

Tissue specificity: Expressed in numerous tissues with highest level in testis

Sequence length: 651 aa · 71836 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.