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Conjugated TDP 43 Rabbit mAb

C52614

Conjugated TDP 43 Rabbit mAb

Human,Mouse,Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Conjugate
AF Dye
UniProt ID
Q13148
Gene
TARDBP
Target organism
Homo sapiens
Catalogue number
C52614
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: TAR DNA-binding protein 43 (TARDBP) · Homo sapiens

RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. Plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondrial transcripts.

Subcellular location: Nucleus; Cytoplasm; Cytoplasm, Stress granule; Mitochondrion

Tissue specificity: Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen

Sequence length: 414 aa · 44740 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.