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Conjugated MiTF Rabbit mAb

C52419

Conjugated MiTF Rabbit mAb

Human,Mouse,Rat Recombinant Rabbit

Conjugated Primary AntibodyHostRecombinant RabbitConjugateAF Dye
Host / source
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Conjugate
AF Dye
UniProt ID
O75030
Gene
MITF
Target organism
Homo sapiens
Catalogue number
C52419
Brand
LABO Scientific
Storage
Store at 4˚Cin dark for 6 months

Target background

Target: Microphthalmia-associated transcription factor (MITF) · Homo sapiens

Transcription factor that acts as a master regulator of melanocyte survival and differentiation as well as melanosome biogenesis. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoter of pigmentation genes, such as tyrosinase (TYR). Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, MITF phosphorylation by MTOR promotes its inactivation. Upon starvation or lysosomal stress, inhibition of MTOR induces MITF dephosphorylation, resulting in transcription factor activity.

Subcellular location: Nucleus; Cytoplasm; Lysosome membrane

Tissue specificity: Expressed in melanocytes (at protein level)

Sequence length: 526 aa · 58795 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4˚Cin dark for 6 months
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.