
C52105
Conjugated Bcl2 Rabbit mAb
Human,Mouse Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human, Mouse
- Conjugate
- AF Dye
- UniProt ID
- P10415
- Gene
- BCL2
- Target organism
- Homo sapiens
- Catalogue number
- C52105
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Apoptosis regulator Bcl-2 (BCL2) · Homo sapiens
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function.
Subcellular location: Mitochondrion outer membrane; Nucleus membrane; Endoplasmic reticulum membrane; Cytoplasm
Tissue specificity: Expressed in a variety of tissues
Sequence length: 239 aa · 26266 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il