C14165
Conjugated Retinoblastoma (Phospho-Ser807) Rabbit mAb
Human Mouse Rat Recombinant Rabbit
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Conjugate
- AF Dye
- UniProt ID
- P06400
- Gene
- RB1
- Target organism
- Homo sapiens
- Catalogue number
- C14165
- Brand
- LABO Scientific
- Storage
- Store at 4˚Cin dark for 6 months
Target background
Target: Retinoblastoma-associated protein (RB1) · Homo sapiens
Tumor suppressor that is a key regulator of the G1/S transition of the cell cycle. The hypophosphorylated form binds transcription regulators of the E2F family, preventing transcription of E2F-responsive genes. Both physically blocks E2Fs transactivating domain and recruits chromatin-modifying enzymes that actively repress transcription. Cyclin and CDK-dependent phosphorylation of RB1 induces its dissociation from E2Fs, thereby activating transcription of E2F responsive genes and triggering entry into S phase.
Subcellular location: Nucleus; Cytoplasm
Tissue specificity: Expressed in the retina. Expressed in foreskin keratinocytes (at protein level)
Sequence length: 928 aa · 106159 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4˚Cin dark for 6 months
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il