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Recombinant Human Interleukin-36 alpha protein(IL36A) (Active)

AP73485

Recombinant Human Interleukin-36 alpha protein(IL36A) (Active)

Recombinant Human Interleukin-36 alpha protein(IL36A) (Active) (catalogue number AP73485) is a e.coli-derived recombinant protein. It targets Interleukin-36 alpha (IL36A): Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Supplied in 3 pack sizes, from 100ug at ₪10,442.02 to 1mg at ₪33,414.48; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostE.Coli
Host / source
E.Coli
UniProt ID
Q9UHA7
Gene
IL36A
Target organism
Homo sapiens
Catalogue number
AP73485
Brand
LABO Scientific
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Target background

Target: Interleukin-36 alpha (IL36A) · Homo sapiens

Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation.

Subcellular location: Cytoplasm; Secreted

Tissue specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin

Sequence length: 158 aa · 17684 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.