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Recombinant Rat Cardiotrophin-1 protein(Ctf1) (Active)

AP73341

Recombinant Rat Cardiotrophin-1 protein(Ctf1) (Active)

Recombinant Rat Cardiotrophin-1 protein(Ctf1) (Active) (catalogue number AP73341) is a e.coli-derived recombinant protein. It targets Cardiotrophin-1 (Ctf1): Functions as a cytokine that binds to the LIF receptor complex. Supplied in 3 pack sizes, from 100ug at ₪8,708.48 to 1mg at ₪27,854.91; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostE.Coli
Host / source
E.Coli
UniProt ID
Q63086
Gene
Ctf1
Target organism
Rattus norvegicus
Catalogue number
AP73341
Brand
LABO Scientific
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Target background

Target: Cardiotrophin-1 (Ctf1) · Rattus norvegicus

Functions as a cytokine that binds to the LIF receptor complex. The LIF receptor complex indeed consists of two signaling receptor subunits IL6ST/gp130 and LIFR that transduce the signal into the cell. Functionnally, acts as a potent cardiac survival factor, and promotes cardiomyocyte proliferation and hypertrophy. Mechanistically, ligand binding to LIFR, induces heterodimerization with IL6ST/gp130 activating JAK tyrosine kinases (JAK1 or JAK2 and to a lesser extent TYK2) bound to their intracellular domains. These kinases subsequently phosphorylate IL6ST/gp130 and LIFR.

Subcellular location: Secreted

Tissue specificity: Expressed in the ventricle and atrium of adult rats. Also detected in the lung, kidney, liver, skeletal muscle, stomach and urinary bladder. Not detected in brain, colon, testis, spleen or thymus. Overexpressed in the ventricles in the case of hypertension and hypertrophy

Sequence length: 203 aa · 21439 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.