
AP73293
Recombinant Human C-C motif chemokine 21 protein(CCL21) (Active)
Recombinant Human C-C motif chemokine 21 protein(CCL21) (Active) (catalogue number AP73293) is a e.coli-derived recombinant protein. It targets C-C motif chemokine 21 (CCL21): Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Supplied in 4 pack sizes, from 20ug at ₪1,370.52 to 1mg at ₪16,066.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- E.Coli
- UniProt ID
- O00585
- Gene
- CCL21
- Target organism
- Homo sapiens
- Catalogue number
- AP73293
- Brand
- LABO Scientific
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Target background
Target: C-C motif chemokine 21 (CCL21) · Homo sapiens
Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Binds to chemokine receptor CCR7. Does not bind to chemokine receptor CXCR3. Binds to G protein-coupled receptor GPR174. Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs
Subcellular location: Secreted
Tissue specificity: Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen
Sequence length: 134 aa · 14646 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il