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Recombinant Human TP53-induced Glycolysis and Apoptosis Regulator

AP60413

Recombinant Human TP53-induced Glycolysis and Apoptosis Regulator

Recombinant Human TP53-induced Glycolysis and Apoptosis Regulator (catalogue number AP60413) is a escherichia coli-derived recombinant protein. It targets Fructose-2,6-bisphosphatase TIGAR (TIGAR): Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪11,412.81; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
Q9NQ88
Gene
TIGAR
Target organism
Homo sapiens
Catalogue number
AP60413
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Fructose-2,6-bisphosphatase TIGAR (TIGAR) · Homo sapiens

Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death.

Subcellular location: Cytoplasm; Nucleus; Mitochondrion

Tissue specificity: Expressed in the brain. Expressed in breast tumors. Expressed in glioblastomas

Sequence length: 270 aa · 30063 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.