
AP60113
Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor
Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (catalogue number AP60113) is a escherichia coli-derived recombinant protein. It targets Mesencephalic astrocyte-derived neurotrophic factor (MANF): Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪11,412.81; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Escherichia coli
- UniProt ID
- P55145
- Gene
- MANF
- Target organism
- Homo sapiens
- Catalogue number
- AP60113
- Brand
- LABO Scientific
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Target background
Target: Mesencephalic astrocyte-derived neurotrophic factor (MANF) · Homo sapiens
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions.
Subcellular location: Secreted; Endoplasmic reticulum lumen; Sarcoplasmic reticulum lumen
Sequence length: 182 aa · 20700 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il