Loading...
Recombinant Human Neuregulin 1-beta1 EGF Domain, 177-241a.a.

AP60109

Recombinant Human Neuregulin 1-beta1 EGF Domain, 177-241a.a.

Recombinant Human Neuregulin 1-beta1 EGF Domain, 177-241a.a. (catalogue number AP60109) is a escherichia coli-derived recombinant protein. It targets Pro-neuregulin-1, membrane-bound isoform (NRG1): Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Supplied in 3 pack sizes, from 10ug at ₪444.60 to 500ug at ₪5,490.22; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
Q02297
Gene
NRG1
Target organism
Homo sapiens
Catalogue number
AP60109
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Pro-neuregulin-1, membrane-bound isoform (NRG1) · Homo sapiens

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor c…

Subcellular location: Cell membrane

Tissue specificity: Type I isoforms are the predominant forms expressed in the endocardium. Isoform alpha is expressed in breast, ovary, testis, prostate, heart, skeletal muscle, lung, placenta liver, kidney, salivary gland, small intestine and brain, but not in uterus, stomach, pancreas, and spleen.

Sequence length: 640 aa · 70392 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.