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Recombinant Human Insulin-like Growth Factor-Binding Protein 5

AP60066

Recombinant Human Insulin-like Growth Factor-Binding Protein 5

Recombinant Human Insulin-like Growth Factor-Binding Protein 5 (catalogue number AP60066) is a escherichia coli-derived growth factor. It targets Insulin-like growth factor-binding protein 5 (IGFBP5): Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪11,412.81; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Growth FactorHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
P24593
Gene
IGFBP5
Target organism
Homo sapiens
Catalogue number
AP60066
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Insulin-like growth factor-binding protein 5 (IGFBP5) · Homo sapiens

Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Increases the cell proliferation of osteoblasts, intestinal smooth muscle cells and neuroblastoma cells. Enhances adhesion and survival of epithelial cells but decreases adhesion of mesenchymal cells. Once secreted, acts as a major mediator of mTORC1-dependent feedback inhibition of IGF1 signaling.

Subcellular location: Secreted; Cytoplasm; Nucleus

Tissue specificity: Osteosarcoma, and at lower levels in liver, kidney and brain

Sequence length: 272 aa · 30570 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.