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Recombinant Human Interleukin-36 gamma, 169a.a.

AP60022

Recombinant Human Interleukin-36 gamma, 169a.a.

Recombinant Human Interleukin-36 gamma, 169a.a. (catalogue number AP60022) is a escherichia coli-derived recombinant protein. It targets Interleukin-36 gamma (IL36G): Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Supplied in 3 pack sizes, from 10ug at ₪1,109.47 to 500ug at ₪19,448.27; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
Q9NZH8
Gene
IL36G
Target organism
Homo sapiens
Catalogue number
AP60022
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Interleukin-36 gamma (IL36G) · Homo sapiens

Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation.

Subcellular location: Cytoplasm; Secreted

Tissue specificity: Highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus. Expressed in bronchial epithelial. In skin is expressed only in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Up-regulated in lesional psoriasis skin.

Sequence length: 169 aa · 18721 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.