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TRIM25 Mouse mAb

64359

TRIM25 Mouse mAb

TRIM25 Mouse mAb (catalogue number 64359) is a mouse-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, Flow cytometry, reactive with Human samples. It targets E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25): Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Western blot Immunohistochemistry Immunofluorescence Flow cytometry
UniProt ID
Q14258
Gene
TRIM25
Target organism
Homo sapiens
Catalogue number
64359
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) · Homo sapiens

Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of RIGI and IFIH1. Mediates 'Lys-63'-linked polyubiquitination of the RIGI N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection. Mediates 'Lys-63'-linked polyubiquitination of IFIH1. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subcellular location: Cytoplasm; Cytoplasm, Stress granule; Nucleus

Tissue specificity: Expressed in breast tumors (at protein level). Ubiquitous

Sequence length: 630 aa · 70973 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.