Loading...
SORL1 Mouse mAb

64265

SORL1 Mouse mAb

SORL1 Mouse mAb (catalogue number 64265) is a mouse-derived primary antibody validated for Immunohistochemistry, Immunofluorescence, reactive with Human samples. It targets Sortilin-related receptor (SORL1): Sorting receptor that directs several proteins to their correct location within the cell (Probable). Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Immunohistochemistry Immunofluorescence
UniProt ID
Q92673
Gene
SORL1
Target organism
Homo sapiens
Catalogue number
64265
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: Sortilin-related receptor (SORL1) · Homo sapiens

Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism.

Subcellular location: Golgi apparatus membrane; Golgi apparatus, trans-Golgi network membrane; Endosome membrane; Early endosome membrane; Recycling endosome membrane; Endoplasmic reticulum membrane; Endosome, multivesicul

Tissue specificity: Highly expressed in brain (at protein level). Most abundant in the cerebellum, cerebral cortex and occipital pole; low levels in the putamen and thalamus. Expression is significantly reduced in the frontal cortex of patients suffering from Alzheimer disease.

Sequence length: 2214 aa · 248426 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.