Loading...
SMAD4 Mouse mAb

64252

SMAD4 Mouse mAb

SMAD4 Mouse mAb (catalogue number 64252) is a mouse-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, Flow cytometry, reactive with Human, Mouse samples. It targets SMAD family member 4 (SMAD4): In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human, Mouse
Applications
Western blot Immunohistochemistry Immunofluorescence Flow cytometry
UniProt ID
Q13485
Gene
SMAD4
Target organism
Homo sapiens
Catalogue number
64252
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: SMAD family member 4 (SMAD4) · Homo sapiens

In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions.

Subcellular location: Cytoplasm; Nucleus

Sequence length: 552 aa · 60439 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.