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PMEL Mouse mAb

64103

PMEL Mouse mAb

PMEL Mouse mAb (catalogue number 64103) is a mouse-derived primary antibody validated for Flow cytometry, reactive with Human samples. It targets Melanocyte protein PMEL (PMEL): Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Flow cytometry
UniProt ID
P40967
Gene
PMEL
Target organism
Homo sapiens
Catalogue number
64103
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: Melanocyte protein PMEL (PMEL) · Homo sapiens

Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation.

Subcellular location: Endoplasmic reticulum membrane; Golgi apparatus, cis-Golgi network membrane; Endosome, multivesicular body; Melanosome; Extracellular vesicle; Secreted

Tissue specificity: Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Overexpressed in melanomas. Some expression was found in dysplastic nevi

Sequence length: 661 aa · 70255 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.