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MTDH Mouse mAb

63960

MTDH Mouse mAb

MTDH Mouse mAb (catalogue number 63960) is a mouse-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, Flow cytometry, reactive with Human, Monkey samples. It targets Protein LYRIC (MTDH): Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human, Monkey
Applications
Western blot Immunohistochemistry Immunofluorescence Flow cytometry
UniProt ID
Q86UE4
Gene
MTDH
Target organism
Homo sapiens
Catalogue number
63960
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: Protein LYRIC (MTDH) · Homo sapiens

Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance

Subcellular location: Endoplasmic reticulum membrane; Nucleus membrane; Cell junction, tight junction; Nucleus, nucleolus; Cytoplasm, perinuclear region

Tissue specificity: Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme

Sequence length: 582 aa · 63837 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.