
63464
CHK1 Mouse mAb
CHK1 Mouse mAb (catalogue number 63464) is a mouse-derived primary antibody validated for Western blot, reactive with Human, Mouse samples. It targets Serine/threonine-protein kinase Chk1 (CHEK1): Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Mouse
- Reactivity
- Human, Mouse
- Applications
- Western blot
- UniProt ID
- O14757
- Gene
- CHEK1
- Target organism
- Homo sapiens
- Catalogue number
- 63464
- Brand
- LABO Scientific
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target background
Target: Serine/threonine-protein kinase Chk1 (CHEK1) · Homo sapiens
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C.
Subcellular location: Nucleus; Chromosome; Cytoplasm; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue specificity: Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon
Sequence length: 476 aa · 54434 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il